Dendritic cell vaccines Paul

نویسندگان

  • Paul J. Mosca
  • Amy C. Hobeika
  • Timothy M. Clay
  • Michael A. Morse
  • H. Kim Lyerly
چکیده

1. Abstract 2. Introduction 3. Preparation of dendritic cells 3.1. Sources of dendritic cells 3.2. Dendritic cell mobilization strategies 3.3. Dendritic cell culture conditions 3.4. Methods of loading dendritic cells with tumor antigens 3.5. Dendritic cell maturation 3.6. The role of helper antigens 3.7. cryopreservation of dendritic cells 4. Administration of dendritic cell vaccines 4.1. Route of dendritic cell administration 4.2. Immunization schedule 4.3. Use of vaccine Adjuvants 4.4. Prime-boost strategy 5. Clinical trials evaluating dendritic cell based cancer vaccines 5.1. Malignant melanoma 5.2. Hematologic malignancies 5.3. Genitourinary tract malignancies 5.4. Gastrointestinal malignancies 5.5. Other malignancies 6. Perspective 7. Acknowledgments 8. Reference

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تاریخ انتشار 2007